Oligonucleotide Synthesis Market: Technological Advancements in Synthetic Chemistry to Drive the Global Market

Wilmington, Delaware, USA, Transparency Market Research Inc. – Transparency Market Research (TMR) has published a new report titled “Oligonucleotide Synthesis Market – Global Industry Analysis, Size, Share, Growth, Trends, and Forecasts, 2019 – 2027”. According to the report, the global market was valued at USD 1,966.2 million in 2018 and is projected to grow at a CAGR of 9.5% from 2019 to 2027.

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An oligonucleotide is a single-stranded chain composed of a number of nucleoside units joined together by the process of phosphodiesterase, which usually synthesizes small fragments on nucleic acid sequences up to 25 bases, with the desired structure and a given sequence needed for different applications.

An oligonucleotide is a single-stranded chain composed of a number of nucleoside units joined together by the process of phosphodiesterase, which usually synthesizes small fragments on nucleic acid sequences up to 25 bases, with the desired structure and a given sequence needed for different applications.

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There are different lengths of oligonucleotides, as well as sequences and design modifications available. With the increasing development of the biotechnology and life science markets, there has been an ever-increasing need for oligonucleotides in the global market, as well as an increasing acceptance and use of oligonucleotides in clinical and diagnostic fields.

Technological advancements in synthetic chemistry to drive the market

Advancements in the technological development of organic molecules are expected to drive the growth of the oligonucleotide synthesis market

Advanced oligonucleotide synthesis provides longer oligos with better sequence fidelity and higher purity that can be used in a number of molecular biology applications

Various pharmaceutical and biotechnology companies are continuously working on the development of new and advanced methods in synthetic chemistry

For example, Integrated DNA Technologies, a leader in synthesized oligonucleotides, has developed various pioneering methods to synthesize oligonucleotides of extreme lengths. The company has developed oligonucleotides up to 200 bases in length that are used with mass spectrometry to make mini-genes.

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Segment of synthesized oligonucleotides to dominate the market

On the basis of product type, the global oligonucleotide synthesis market has been divided into reagents and consumables, equipment, and synthesized oligonucleotides. The synthesized oligonucleotide segment has been divided into DNA oligonucleotides, RNA oligonucleotides and others.

The synthesized oligonucleotides segment dominated the global oligonucleotide synthesis market in 2018 and the trend is expected to continue during the forecast period. The synthesized oligonucleotides are widely used in research as well as in therapeutic and diagnostic applications. The synthesized oligonucleotides are ready-to-use oligonucleotides. These are also available as custom oligos prepared as needed. There are two types of synthesized oligonucleotides used commercially: DNA oligonucleotides and RNA oligonucleotides. Bridged nucleic acid (BNA) and locked nucleic acid (LNA) are the other types of synthesized oligonucleotides used in research.

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Search apps must be a very lucrative segment

In terms of application, the global oligonucleotide synthesis market has been categorized into research, diagnostics and therapeutics. Among applications, the research application segment dominated the global oligonucleotide synthesis market in 2018. The increasing emphasis on R&D by pharmaceutical and biotechnology companies, along with technological advancements in techniques such as the reaction in polymerase chain and next-generation sequencing, are some of the major factors driving the growth of the research segment in 2018. However, increasing applications in therapeutics and growing R&D in RNAi therapeutic drugs are expected to driving the growth of the therapeutic segment during the period 2019-2027

North America will dominate the global market

In terms of region, the global oligonucleotide synthesis market has been segmented into North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. North America led the global oligonucleotide synthesis market in 2018, followed by Europe.

North America accounted for a significant share of the global oligonucleotide synthesis market in 2018. According to data obtained from ongoing clinical trials in the oligonucleotide segment, there were more than 70 oligonucleotide trials ongoing or recently completed in the United States alone. The rapidly growing life sciences industry, the growing attention to genetics and genomics in research and diagnostic applications in North America, and the growing interest of pharmaceutical organizations in oligonucleotides as Therapeutic agents including RNAi and antisense therapies are driving demand for oligonucleotides in North America.

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However, the increasing focus on personalized medicine and the growth of biotechnology and life science research activities in Asia-Pacific, as well as increased healthcare spending on research and development in India, China and in Japan are factors that are expected to drive the growth of the oligonucleotide synthesis market in Asia. Pacific from 2019 to 2027.

Competitive landscape

The global oligonucleotide synthesis market is fragmented in number of players. The major players in the global market are GE Healthcare, Thermo Fischer Scientific, Agilent Technologies, Inc., Merck KGaA, Integrated DNA Technologies, Inc., Kaneka Eurogentec SA, BioAutomation, Gene Design, Inc., Eurofins Genomics, and ATDBio, Ltd. among others.

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